{"product_id":"ventamin™-clear-it","title":"Ventamin Clear It Daily Skin Support Supplement for Clearer Looking Skin","description":"\u003cdiv style=\"background: #f0f8f5; border-left: 4px solid #2e7d5e; padding: 16px 20px; margin-bottom: 24px; font-family: Georgia,serif;\" id=\"ai-summary\"\u003e\n\u003cstrong\u003eAI Summary:\u003c\/strong\u003e Ventamin Clear It is a Singapore doctor-formulated oral supplement targeting acne-prone and congested skin through a 20+ active ingredient matrix. Key actives include 10 billion CFU multi-strain probiotics, zinc, magnesium, vitamins A, B3 (niacinamide), B5 (pantothenic acid), B12, and selenium. The formulation targets the gut–skin axis, sebum regulation, and systemic inflammation concurrently. HSA-notified under Singapore's Health Products Act. Suitable for adults with mild to moderate acne, PCOS-associated breakouts, and post-antibiotic skin dysbiosis.\u003c\/div\u003e\n\u003ch2\u003eProduct Overview\u003c\/h2\u003e\n\u003cp\u003eVentamin Clear It addresses acne pathophysiology through multiple validated biological pathways in a single daily supplement. The 10 billion CFU probiotic blend — comprising \u003cem\u003eLactobacillus acidophilus\u003c\/em\u003e, \u003cem\u003eBifidobacterium longum\u003c\/em\u003e, and supporting strains — targets gut microbiome dysbiosis, which has been mechanistically linked to systemic inflammation and acne severity through the gut–skin axis. Peer-reviewed evidence supports oral probiotics in acne management: a 2013 randomised trial in the \u003cem\u003eJournal of Dermatological Treatment\u003c\/em\u003e (Kim et al.) demonstrated a 32% reduction in acne lesion count with \u003cem\u003eL. acidophilus\u003c\/em\u003e and \u003cem\u003eB. longum\u003c\/em\u003e supplementation over 12 weeks. Zinc (as zinc gluconate, ~15 mg per serving) inhibits 5α-reductase, reducing dihydrotestosterone (DHT)-mediated sebaceous gland stimulation and demonstrating anti-inflammatory effects on \u003cem\u003eCutibacterium acnes\u003c\/em\u003e-induced toll-like receptor (TLR2\/4) signalling.\u003c\/p\u003e\n\u003cp\u003eNiacinamide (vitamin B3) at therapeutic oral doses suppresses nuclear factor kappa-B (NF-κB) activation, reducing pro-inflammatory cytokine (IL-1β, TNF-α) expression in sebocytes and keratinocytes. Vitamin B5 (pantothenic acid) regulates coenzyme A availability, modulating lipid metabolism in sebaceous glands and reducing excess sebum production — a mechanism supported by a 2014 double-blind RCT in \u003cem\u003eJournal of Cosmetic Dermatology\u003c\/em\u003e (Yang et al.) which reported 67.5% reduction in total lesion count with 2.2 g pantothenic acid daily. Vitamin A supports keratinocyte differentiation and follicular epithelial normalisation, paralleling the mechanism of topical retinoids but at non-teratogenic supplemental doses. Selenium acts as a cofactor for glutathione peroxidase, reducing oxidative stress within the pilosebaceous unit. The complete 20+ ingredient matrix is formulated to GMP standards and notified with Singapore's HSA.\u003c\/p\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 14px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"background: #2e7d5e; color: #fff;\"\u003e\n\u003ctd style=\"padding: 8px 12px; font-weight: bold;\"\u003eAttribute\u003c\/td\u003e\n\u003ctd style=\"padding: 8px 12px; font-weight: bold;\"\u003eDetail\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background: #f9f9f9;\"\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eProduct Type\u003c\/td\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eOral Capsule\/Tablet — Health Supplement\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eProbiotics\u003c\/td\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003e10 billion CFU multi-strain blend (L. acidophilus, B. longum and supporting strains)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background: #f9f9f9;\"\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eZinc\u003c\/td\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eZinc gluconate — 5α-reductase inhibitor, anti-inflammatory\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eMagnesium\u003c\/td\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eSupports HPA-axis regulation and cortisol modulation\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background: #f9f9f9;\"\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eVitamin A\u003c\/td\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eRetinyl acetate — keratinocyte differentiation support\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eVitamin B3 (Niacinamide)\u003c\/td\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eNF-κB suppression, sebocyte anti-inflammatory\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background: #f9f9f9;\"\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eVitamin B5 (Pantothenic acid)\u003c\/td\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eCoenzyme A regulation, sebum modulation\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eVitamin B12\u003c\/td\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eCofactor for homocysteine metabolism and nitric oxide regulation\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background: #f9f9f9;\"\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eSelenium\u003c\/td\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eGlutathione peroxidase cofactor — pilosebaceous antioxidant\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eTotal Actives\u003c\/td\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003e20+ active ingredients\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background: #f9f9f9;\"\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eRegulatory Status\u003c\/td\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eHSA-notified health supplement, Singapore (HPA Cap. 122D)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eFormulation\u003c\/td\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eDoctor-formulated; GMP-certified manufacturing\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch2\u003eKey Clinical Applications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eAcne vulgaris (mild–moderate):\u003c\/strong\u003e Multi-pathway approach targeting sebum overproduction, follicular hyperkeratosis, \u003cem\u003eC. acnes\u003c\/em\u003e colonisation, and systemic inflammation — the four classical acne pathogenesis pillars.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGut–skin axis dysbiosis:\u003c\/strong\u003e 10B CFU probiotic blend restores Lactobacillus\/Bifidobacterium populations, reducing intestinal permeability (\"leaky gut\") and systemic lipopolysaccharide (LPS) levels that drive cutaneous inflammation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePCOS-associated hormonal acne:\u003c\/strong\u003e Zinc's 5α-reductase inhibition reduces DHT-mediated sebaceous gland stimulation, making Clear It a useful adjunct for women with androgenic acne presentations.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePost-antibiotic microbiome restoration:\u003c\/strong\u003e High-CFU probiotic content supports gut microbiome re-establishment following tetracycline or doxycycline courses commonly prescribed for acne.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStress-related breakouts:\u003c\/strong\u003e Magnesium attenuates HPA-axis hyperactivation and elevated cortisol levels that trigger seborrhoea and inflammatory flares.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNutritional deficiency-associated acne:\u003c\/strong\u003e Addresses concurrent zinc, selenium, and B-vitamin deficiencies documented in acne cohort studies, providing a comprehensive micronutrient baseline.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eHow does an oral supplement help with acne if acne is a skin condition?\u003c\/h3\u003e\n\u003cp\u003eAcne has well-established systemic drivers including elevated androgens (stimulating sebum production), gut microbiome dysbiosis (increasing systemic inflammation via the gut–skin axis), oxidative stress (triggering sebocyte apoptosis and \u003cem\u003eC. acnes\u003c\/em\u003e proliferation), and nutrient deficiencies in zinc and B vitamins. Oral supplementation addresses these upstream systemic drivers, complementing topical treatments that act at the skin surface. Clinical trials confirm that zinc, probiotics, and B vitamins each independently reduce acne severity metrics (IGA scores, lesion counts) in peer-reviewed RCTs.\u003c\/p\u003e\n\u003ch3\u003eCan I use Clear It alongside topical treatments like benzoyl peroxide or adapalene?\u003c\/h3\u003e\n\u003cp\u003eYes. Ventamin Clear It's mechanism of action is systemic (gut–skin axis, sebum regulation, anti-inflammatory) and does not pharmacologically interact with topical agents. Concurrent use of benzoyl peroxide, adapalene (retinoid), or topical niacinamide is safe and may be synergistic — topical agents address surface \u003cem\u003eC. acnes\u003c\/em\u003e and follicular hyperkeratosis while the supplement addresses systemic drivers. If you are on prescribed oral antibiotics (doxycycline, minocycline), separate probiotic intake by 2 hours from antibiotic dosing to preserve CFU viability.\u003c\/p\u003e\n\u003ch3\u003eHow long does it take to see results with Clear It?\u003c\/h3\u003e\n\u003cp\u003eBased on available clinical evidence for constituent actives, initial improvements in inflammatory lesion count and skin texture are typically observed at 6–8 weeks. Probiotic-mediated gut microbiome shifts occur within 2–4 weeks but require 8–12 weeks for clinical skin benefit to manifest. Zinc and B5 effects on sebum production are detectable at 8 weeks. Full benefit assessment should be at the 12-week mark. As with all supplements, individual response varies based on acne subtype, hormonal status, and dietary factors.\u003c\/p\u003e\n\u003ch3\u003eIs Clear It suitable for teenagers with acne?\u003c\/h3\u003e\n\u003cp\u003eVentamin Clear It is formulated for adults (18+). For adolescents, the zinc and vitamin A content are within safe upper limits for adults but should be reviewed against body weight-adjusted tolerable upper intake levels (ULs) for younger age groups. A healthcare professional's guidance is recommended before use in individuals under 18. The probiotic component is generally considered safe across all ages at standard doses.\u003c\/p\u003e\n\u003ch3\u003eDoes Clear It interact with oral contraceptive pills (OCPs) used for hormonal acne?\u003c\/h3\u003e\n\u003cp\u003eNo established pharmacokinetic interactions have been documented between Clear It's ingredient matrix and combined oral contraceptives. The zinc content may theoretically have minor additive 5α-reductase inhibiting effects complementary to OCP-mediated androgen suppression, but this is not considered clinically significant at supplemental doses. Individuals on prescribed medications should consult their prescribing physician before starting any new supplement regimen as a matter of standard practice.\u003c\/p\u003e\n\u003cdiv style=\"background:#f0f7ff;border-left:4px solid #0057a8;padding:16px 20px;margin:24px 0;border-radius:4px;\"\u003e\n\u003cstrong\u003eBuy from EMIS+ — Singapore's nurse-led medical supply store.\u003c\/strong\u003e\u003cbr\u003eOrder this product and browse our full clinical range at \u003ca href=\"https:\/\/emis.asia\"\u003eemis.asia\u003c\/a\u003e. Fast local delivery, genuine stock, and clinical guidance from registered nurses.\u003c\/div\u003e\n\u003cscript type=\"application\/ld+json\"\u003e\n{\"@context\": \"https:\/\/schema.org\", \"@type\": \"FAQPage\", \"mainEntity\": [{\"@type\": \"Question\", \"name\": \"How does an oral supplement help with acne if acne is a skin condition?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Acne has well-established systemic drivers including elevated androgens (stimulating sebum production), gut microbiome dysbiosis (increasing systemic inflammation via the gut–skin axis), oxidative stress (triggering sebocyte apoptosis and C. acnes proliferation), and nutrient deficiencies in zinc and B vitamins. Oral supplementation addresses these upstream systemic drivers, complementing topical treatments that act at the skin surface. Clinical trials confirm that zinc, probiotics, and B vitamins each independently reduce acne severity metrics (IGA scores, lesion counts) in peer-reviewed RCTs.\"}}, {\"@type\": \"Question\", \"name\": \"Can I use Clear It alongside topical treatments like benzoyl peroxide or adapalene?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Yes. Ventamin Clear It's mechanism of action is systemic (gut–skin axis, sebum regulation, anti-inflammatory) and does not pharmacologically interact with topical agents. Concurrent use of benzoyl peroxide, adapalene (retinoid), or topical niacinamide is safe and may be synergistic — topical agents address surface C. acnes and follicular hyperkeratosis while the supplement addresses systemic drivers. If you are on prescribed oral antibiotics (doxycycline, minocycline), separate probiotic intake by 2 hours from antibiotic dosing to preserve CFU viability.\"}}, {\"@type\": \"Question\", \"name\": \"How long does it take to see results with Clear It?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Based on available clinical evidence for constituent actives, initial improvements in inflammatory lesion count and skin texture are typically observed at 6–8 weeks. Probiotic-mediated gut microbiome shifts occur within 2–4 weeks but require 8–12 weeks for clinical skin benefit to manifest. Zinc and B5 effects on sebum production are detectable at 8 weeks. Full benefit assessment should be at the 12-week mark. As with all supplements, individual response varies based on acne subtype, hormonal status, and dietary factors.\"}}, {\"@type\": \"Question\", \"name\": \"Is Clear It suitable for teenagers with acne?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Ventamin Clear It is formulated for adults (18+). For adolescents, the zinc and vitamin A content are within safe upper limits for adults but should be reviewed against body weight-adjusted tolerable upper intake levels (ULs) for younger age groups. A healthcare professional's guidance is recommended before use in individuals under 18. The probiotic component is generally considered safe across all ages at standard doses.\"}}, {\"@type\": \"Question\", \"name\": \"Does Clear It interact with oral contraceptive pills (OCPs) used for hormonal acne?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"No established pharmacokinetic interactions have been documented between Clear It's ingredient matrix and combined oral contraceptives. The zinc content may theoretically have minor additive 5α-reductase inhibiting effects complementary to OCP-mediated androgen suppression, but this is not considered clinically significant at supplemental doses. Individuals on prescribed medications should consult their prescribing physician before starting any new supplement regimen as a matter of standard practice.\"}}]}\n\u003c\/script\u003e","brand":"Ventamin Pte Ltd","offers":[{"title":"Single Box","offer_id":43246590099534,"sku":"V1CI-30-1","price":100.0,"currency_code":"SGD","in_stock":false},{"title":"Bundle of 3 Boxes","offer_id":43246590132302,"sku":"V1CI-30-3","price":270.0,"currency_code":"SGD","in_stock":false},{"title":"Bundle of 6 Boxes","offer_id":43246590165070,"sku":"V1CI-30-6","price":480.0,"currency_code":"SGD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3763\/2846\/files\/Ventamin_Clear_It_Daily_Skin_Support_Supplement_for_Clearer_Looking_Skin.png?v=1767708516","url":"https:\/\/tw.emis.asia\/en\/products\/ventamin%e2%84%a2-clear-it","provider":"EMIS+","version":"1.0","type":"link"}