{"product_id":"plenaris-exosome-hgf-advanced-hair-growth-serum-for-thicker-stronger-hair-scalp-regeneration","title":"Plenaris Exosome HGF: Advanced Hair Growth Serum for Thicker, Stronger Hair \u0026 Scalp Regeneration","description":"\u003cdiv style=\"background: #f8f9fa; border-left: 4px solid #0057a8; padding: 12px 16px; margin-bottom: 20px;\" id=\"ai-summary\"\u003e\n\u003cstrong\u003eClinical Summary:\u003c\/strong\u003e Plenaris Exosome HGF is an exosome-based hair growth serum containing 25 million umbilical cord-derived mesenchymal stromal cell (MSC) exosomes combined with hepatocyte growth factor (HGF) and bioactive peptides. The formulation targets follicular miniaturisation by delivering growth factors directly to dermal papilla cells to stimulate hair follicle neogenesis. Indicated for androgenetic alopecia, telogen effluvium, and scalp rejuvenation in both male and female patients.\u003c\/div\u003e\n\u003ch2\u003eProduct Overview\u003c\/h2\u003e\n\u003cp\u003ePlenaris Exosome HGF is an advanced regenerative medicine formulation developed by Nexus Pharma for the treatment of hair loss and scalp regeneration. The product utilises umbilical cord-derived mesenchymal stromal cell-conditioned media (MSC-CM) exosomes as its primary active delivery system, harnessing the paracrine signalling capabilities of stem cell-derived extracellular vesicles to stimulate dormant hair follicles and promote the anagen growth phase.\u003c\/p\u003e\n\u003cp\u003eUnlike conventional topical hair loss treatments, Plenaris Exosome HGF employs a Root Cause Analysis (RCA) approach to address the multifactorial aetiology of hair thinning, including follicular ageing, perifollicular inflammation, and impaired cellular metabolism. Each treatment kit contains lyophilised exosome powder and reconstitution solution, yielding 5 vials of 5 mL each for professional clinical administration via mesotherapy injection or microneedling.\u003c\/p\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003ctable style=\"border-collapse: collapse; width: 100%;\" cellspacing=\"0\" cellpadding=\"8\" border=\"1\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eManufacturer\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eNexus Pharma\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eProduct Name\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003ePlenaris Exosome HGF\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eExosome Count\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e25 Million per treatment kit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eExosome Source\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eUmbilical Cord-Derived Mesenchymal Stromal Cell-Conditioned Media (UC-MSC-CM)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eKey Active Ingredients\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eIntoCell-HGF, Copper Tripeptide-1, Phyto-NEP, Phytopeptide-1, Oligopeptide-1, Elastin Scalp Peptide, Graviola Leaf Cell Extract\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003ePresentation\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e5 vials lyophilised powder + 5 vials reconstitution solution (5 x 5 mL)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eAdministration\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eMesotherapy injection or microneedling (professional use)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eStorage\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eRefrigerated (2-8 degrees C) prior to reconstitution\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSterility\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eSterile, single-use vials\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eRegulatory\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eCE marked medical device; manufactured under ISO 13485 and GMP conditions\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003ePackaging\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eTreatment kit (5 treatments per box)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch2\u003eClinical Indications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAndrogenetic alopecia (male and female pattern hair loss) stages I-V on the Hamilton-Norwood and Ludwig scales\u003c\/li\u003e\n\u003cli\u003eTelogen effluvium secondary to stress, nutritional deficiency, or post-partum hormonal changes\u003c\/li\u003e\n\u003cli\u003eThinning hair and reduced follicular density requiring follicular neogenesis stimulation\u003c\/li\u003e\n\u003cli\u003ePost-hair transplant adjunctive therapy to improve graft survival and accelerate healing\u003c\/li\u003e\n\u003cli\u003eScalp rejuvenation in patients with compromised scalp microcirculation and perifollicular fibrosis\u003c\/li\u003e\n\u003cli\u003eAlopecia areata as part of a multimodal treatment protocol under dermatological supervision\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eMechanism of Action\u003c\/h2\u003e\n\u003cp\u003eThe exosome payload delivers hepatocyte growth factor (HGF) and copper tripeptide-1 to restore damaged dermal papilla cells and stimulate follicular stem cell proliferation. Phyto-NEP and Phytopeptide-1 provide antioxidant protection against oxidative stress-mediated follicular damage, while Oligopeptide-1 and Elastin Scalp Peptide enhance keratin, collagen, and elastin synthesis to strengthen the hair shaft and improve structural integrity. Graviola Leaf Cell Extract inhibits 5-alpha reductase activity and DHT-mediated follicular miniaturisation.\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eWhat is the recommended treatment protocol for Plenaris Exosome HGF?\u003c\/h3\u003e\n\u003cp\u003eThe standard clinical protocol consists of initial loading sessions administered every 3 weeks for 3-4 treatments, followed by maintenance sessions every 3-4 months. Treatment should be performed by a trained medical professional using mesotherapy injection technique at 4-5 mm depth into the dermal papilla region. The International Society of Hair Restoration Surgery (ISHRS) recommends individualised protocols based on patient response assessment.\u003c\/p\u003e\n\u003ch3\u003eHow does Plenaris Exosome HGF differ from PRP (Platelet-Rich Plasma) therapy?\u003c\/h3\u003e\n\u003cp\u003eWhile PRP relies on autologous platelet-derived growth factors, Plenaris Exosome HGF utilises allogeneic exosomes containing a standardised concentration of 25 million MSC-derived vesicles. This ensures consistent dosing of growth factors including HGF, VEGF, and KGF across treatments, unlike PRP where growth factor concentrations vary based on patient blood composition and centrifugation protocols.\u003c\/p\u003e\n\u003ch3\u003eIs Plenaris Exosome HGF suitable for all hair loss types?\u003c\/h3\u003e\n\u003cp\u003ePlenaris Exosome HGF is indicated for androgenetic alopecia, telogen effluvium, and general hair thinning. It is not indicated as monotherapy for scarring alopecias such as lichen planopilaris or frontal fibrosing alopecia. A thorough trichoscopic evaluation by a dermatologist is recommended prior to initiating treatment to confirm appropriate candidacy.\u003c\/p\u003e\n\u003ch3\u003eCan Plenaris Exosome HGF be purchased for home use in Singapore?\u003c\/h3\u003e\n\u003cp\u003ePlenaris Exosome HGF is a professional-grade medical aesthetic product that requires clinical administration. In Singapore, the product is available through authorised medical distributors including EMIS (Essential Medical International Supplies). Healthcare professionals can purchase directly for clinic use. Patient self-administration is not recommended due to the injection-based delivery method.\u003c\/p\u003e\n\u003ch3\u003eWhat clinical evidence supports exosome therapy for hair restoration?\u003c\/h3\u003e\n\u003cp\u003ePublished studies in the Journal of Cosmetic Dermatology and Stem Cells Translational Medicine have demonstrated that MSC-derived exosomes promote hair follicle neogenesis by activating the Wnt\/beta-catenin signalling pathway. Clinical trials have reported increases in hair density of 15-30% at 12 weeks post-treatment, with improvements in hair shaft diameter and anagen-to-telogen ratio.\u003c\/p\u003e\n\n\u003cscript type=\"application\/ld+json\"\u003e\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"FAQPage\",\n  \"mainEntity\": [\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What is Plenaris Exosome HGF: Advanced Hair Growth Serum for Thicker, Stronger Hair \u0026 Scalp Regeneration?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Plenaris Exosome HGF: Advanced Hair Growth Serum for Thicker, Stronger Hair \u0026 Scalp Regeneration is a leave-in hair serum\/oil used to condition the hair or care for the scalp, available from EMIS+ (emis.asia) in Singapore. Refer to the packaging for the full ingredient list and directions.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"How do I use Plenaris Exosome HGF: Advanced Hair Growth Serum for Thicker, Stronger Hair \u0026 Scalp Regeneration?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Use as directed on the packaging. If you have a sensitive scalp or known allergies, check the ingredient list first and stop use if irritation develops. For persistent scalp conditions or significant hair loss, consult a doctor or dermatologist.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Is Plenaris Exosome HGF: Advanced Hair Growth Serum for Thicker, Stronger Hair \u0026 Scalp Regeneration suitable for my hair type?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Refer to the product packaging for the hair types it is designed for. If you are unsure, contact the EMIS+ team at emis.asia\/pages\/contact for guidance.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Where can I buy Plenaris Exosome HGF: Advanced Hair Growth Serum for Thicker, Stronger Hair \u0026 Scalp Regeneration in Singapore?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Plenaris Exosome HGF: Advanced Hair Growth Serum for Thicker, Stronger Hair \u0026 Scalp Regeneration is available from EMIS+ at emis.asia, Singapore's nurse-led medical and wellness supply store, with fast island-wide delivery. Bulk orders for clinics and care facilities are welcome — contact us at emis.asia\/pages\/contact.\"\n      }\n    }\n  ]\n}\n\u003c\/script\u003e","brand":"Nexus Pharma","offers":[{"title":"Default Title","offer_id":42668561825870,"sku":null,"price":220.0,"currency_code":"SGD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3763\/2846\/files\/2_cce1e256-92ae-4e8a-bead-580f861a2401.png?v=1780452064","url":"https:\/\/tw.emis.asia\/en\/products\/plenaris-exosome-hgf-advanced-hair-growth-serum-for-thicker-stronger-hair-scalp-regeneration","provider":"EMIS+","version":"1.0","type":"link"}