{"product_id":"c-e-ferulic-vitamin-c-serum-drmsj","title":"SkinCeuticals C E Ferulic® Vitamin C Serum","description":"\u003cdiv style=\"background: #f8f9fa; border-left: 4px solid #0057a8; padding: 12px 16px; margin-bottom: 20px;\" id=\"ai-summary\"\u003e\n\u003cstrong\u003eClinical Summary:\u003c\/strong\u003e SkinCeuticals C E Ferulic® is a clinically validated daytime antioxidant serum containing 15% L-ascorbic acid, 1% alpha-tocopherol (vitamin E), and 0.5% ferulic acid formulated at pH 2.5–3.0 to maximise vitamin C stability and dermal penetration. The combination synergistically doubles photoprotection against UVA\/UVB-induced oxidative damage, stimulates collagen biosynthesis, and reduces the appearance of fine lines, wrinkles, and hyperpigmentation. Available in Singapore from EMIS; suitable for dermatology clinic retail, aesthetic practice dispensaries, and prescription-grade skincare programmes. The formula is protected under SkinCeuticals' patented antioxidant composition technology and manufactured under ISO 22716:2007 (GMP for cosmetics) standards.\u003c\/div\u003e\n\u003ch2\u003eProduct Overview\u003c\/h2\u003e\n\u003cp\u003eSkinCeuticals C E Ferulic® is the originator antioxidant serum that established the clinical standard for topical vitamin C therapy in dermatology. The product's efficacy rests on the synergistic interaction among its three active antioxidant components: 15% L-ascorbic acid provides direct free radical neutralisation and stimulates pro-collagen I and III synthesis in human fibroblasts; 1% alpha-tocopherol (vitamin E) regenerates oxidised vitamin C and provides independent lipid-soluble antioxidant activity; and 0.5% ferulic acid — a hydroxycinnamic acid derivative — further doubles the combined photoprotective efficacy of the vitamins C and E combination while also stabilising the formulation. The aqueous vehicle is buffered to pH 2.5–3.0, which is critical for maintaining L-ascorbic acid in its bioavailable, uncharged form to facilitate passive diffusion across the stratum corneum into the viable epidermis.\u003c\/p\u003e\n\u003cp\u003eIn Singapore, topical cosmeceutical serums containing L-ascorbic acid are regulated as cosmetics under the ASEAN Cosmetic Directive (ACD) harmonised framework, enforced by the Health Sciences Authority (HSA) under the Health Products Act (Cap. 122D). SkinCeuticals C E Ferulic® is an internationally distributed product manufactured under ISO 22716:2007 Cosmetics Good Manufacturing Practices (GMP), and retailed through authorised dermatology clinics, aesthetic medical practices, and cosmeceutical suppliers including EMIS in Singapore. The product is not classified as a pharmaceutical and does not require Therapeutic Products registration under the HSA Therapeutic Products regulatory pathway.\u003c\/p\u003e\n\u003ch2\u003eProduct Specifications\u003c\/h2\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; margin-bottom: 20px;\"\u003e\n\u003cthead\u003e\n\u003ctr style=\"background: #0057a8; color: #fff;\"\u003e\n\u003cth style=\"padding: 8px; text-align: left;\"\u003eParameter\u003c\/th\u003e\n\u003cth style=\"padding: 8px; text-align: left;\"\u003eSpecification\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n\u003ctd style=\"padding: 8px;\"\u003eBrand \/ Manufacturer\u003c\/td\u003e\n\u003ctd style=\"padding: 8px;\"\u003eSkinCeuticals (L'Oréal Group)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd; background: #f9f9f9;\"\u003e\n\u003ctd style=\"padding: 8px;\"\u003eActive Ingredients\u003c\/td\u003e\n\u003ctd style=\"padding: 8px;\"\u003e15% L-Ascorbic Acid, 1% Alpha-Tocopherol, 0.5% Ferulic Acid\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n\u003ctd style=\"padding: 8px;\"\u003eFormulation pH\u003c\/td\u003e\n\u003ctd style=\"padding: 8px;\"\u003e2.5–3.0 (optimal for L-ascorbic acid dermal penetration)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd; background: #f9f9f9;\"\u003e\n\u003ctd style=\"padding: 8px;\"\u003eProduct Volume\u003c\/td\u003e\n\u003ctd style=\"padding: 8px;\"\u003e30 ml\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n\u003ctd style=\"padding: 8px;\"\u003eProduct Format\u003c\/td\u003e\n\u003ctd style=\"padding: 8px;\"\u003eAqueous serum; dropper applicator\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd; background: #f9f9f9;\"\u003e\n\u003ctd style=\"padding: 8px;\"\u003eApplication\u003c\/td\u003e\n\u003ctd style=\"padding: 8px;\"\u003eDaytime antioxidant serum; apply to cleansed face\/neck before moisturiser and SPF\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n\u003ctd style=\"padding: 8px;\"\u003eSkin Types\u003c\/td\u003e\n\u003ctd style=\"padding: 8px;\"\u003eNormal, dry, and sensitive skin (optimised for this phenotype)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd; background: #f9f9f9;\"\u003e\n\u003ctd style=\"padding: 8px;\"\u003eManufacturing Standard\u003c\/td\u003e\n\u003ctd style=\"padding: 8px;\"\u003eISO 22716:2007 Cosmetics GMP\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n\u003ctd style=\"padding: 8px;\"\u003eRegulatory Classification (SG)\u003c\/td\u003e\n\u003ctd style=\"padding: 8px;\"\u003eCosmetic product; ASEAN Cosmetic Directive; HSA-notified cosmetic\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd; background: #f9f9f9;\"\u003e\n\u003ctd style=\"padding: 8px;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 8px;\"\u003eDiscard within 3 months of opening; store away from direct sunlight\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch2\u003eClinical Indications and Key Applications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eEnvironmental oxidative stress protection:\u003c\/strong\u003e Topical application before UV and pollution exposure neutralises free radicals in the epidermis and dermis, supplementing but not replacing SPF sunscreen protection. Research demonstrates that the C + E + ferulic acid combination provides 8-fold photoprotection compared to unprotected skin, and doubles the protection of C + E alone.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePost-inflammatory hyperpigmentation and dyschromia:\u003c\/strong\u003e L-ascorbic acid inhibits tyrosinase-mediated melanin synthesis, supporting brightening of post-acne marks, melasma, and solar lentigines over a 12-week treatment course. Used as an adjunct to dermatologist-prescribed depigmentation regimens.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCollagen stimulation and anti-aging:\u003c\/strong\u003e L-ascorbic acid is an essential co-factor for prolyl hydroxylase and lysyl hydroxylase enzymes required for collagen cross-linking. Clinical studies on topical L-ascorbic acid demonstrate increased collagen I and III mRNA expression and reduced fine line appearance over 12 weeks of consistent use.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePre- and post-procedure skin conditioning:\u003c\/strong\u003e Prescribed by dermatologists and aesthetic physicians in Singapore for pre-laser brightening protocols and post-procedure barrier support, in conjunction with post-procedure serums such as SkinCeuticals Phyto Corrective or HA Intensifier.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClinic retail and aesthetic practice dispensary:\u003c\/strong\u003e Supplied to Singapore dermatology clinics, aesthetic medical practices, and specialist skin clinics as a clinic-dispensed cosmeceutical supporting patient treatment adherence and in-clinic product revenue.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cdl\u003e\n\u003cdt\u003e\u003cstrong\u003eWhy must the pH be 2.5–3.0 for vitamin C to work?\u003c\/strong\u003e\u003c\/dt\u003e\n\u003cdd\u003eL-ascorbic acid exists in its uncharged (reduced) form at pH below 3.5, which is the form required to passively diffuse through the lipid-rich stratum corneum into the viable epidermis. At higher pH, L-ascorbic acid ionises and loses its ability to penetrate skin. The pH 2.5–3.0 window also maximises L-ascorbic acid chemical stability, reducing its rapid oxidative degradation to inactive dehydroascorbic acid. Ferulic acid additionally acts as a stabilising agent within this pH range.\u003c\/dd\u003e\n\u003cdt\u003e\u003cstrong\u003eHow does C E Ferulic differ from other vitamin C serums on the market?\u003c\/strong\u003e\u003c\/dt\u003e\n\u003cdd\u003eMany vitamin C serums use derivatives such as ascorbyl glucoside, ascorbyl palmitate, or magnesium ascorbyl phosphate, which must undergo enzymatic conversion to L-ascorbic acid in the skin. SkinCeuticals C E Ferulic® uses the direct, pure L-ascorbic acid form at 15% — the highest clinically effective concentration before diminishing returns and irritation risk — combined with the ferulic acid potentiator. This formulation is backed by peer-reviewed research and Duke University patent protection (US 7,179,841).\u003c\/dd\u003e\n\u003cdt\u003e\u003cstrong\u003eIs this product suitable for post-laser or post-peel skin in Singapore's climate?\u003c\/strong\u003e\u003c\/dt\u003e\n\u003cdd\u003eDuring the immediate post-procedure healing phase (first 3–5 days post-ablative laser), the barrier is compromised and acidic serums should be withheld to avoid irritation. From day 5–7 onward, once re-epithelialisation is confirmed, C E Ferulic® can be reintroduced as part of a physician-directed antioxidant maintenance protocol. Singapore's tropical climate increases cumulative UV exposure, making daily antioxidant serum use particularly relevant for photoprotection maintenance between clinic visits.\u003c\/dd\u003e\n\u003cdt\u003e\u003cstrong\u003eIs SkinCeuticals C E Ferulic® regulated by HSA in Singapore?\u003c\/strong\u003e\u003c\/dt\u003e\n\u003cdd\u003eThe product is classified as a cosmetic under the ASEAN Cosmetic Directive (ACD), which Singapore enforces under the Health Products Act. Cosmetics under the ACD are notified rather than registered, meaning the responsible person notifies HSA prior to market placement. L-ascorbic acid at cosmetic-grade concentrations is a permitted cosmetic ingredient under the ACD Annex framework. It does not require Therapeutic Products or Medical Device registration. EMIS supplies the product for clinic-dispensed cosmeceutical procurement.\u003c\/dd\u003e\n\u003cdt\u003e\u003cstrong\u003eHow should the serum be stored to prevent oxidation?\u003c\/strong\u003e\u003c\/dt\u003e\n\u003cdd\u003eL-ascorbic acid oxidises on exposure to air, light, and heat. Store C E Ferulic® at room temperature (18–25°C), away from direct sunlight, and ensure the dropper cap is tightly sealed after each use. An amber or opaque bottle — as used in SkinCeuticals packaging — reduces photodegradation. Discard 3 months after opening or if the solution turns orange or brown, indicating significant oxidation to dehydroascorbic acid, which has no antioxidant activity. Do not refrigerate.\u003c\/dd\u003e\n\u003c\/dl\u003e\n\u003cp\u003e\u003cem\u003eAvailable from EMIS for Singapore clinic procurement and individual purchase. Orders placed before 12:00 SGT are dispatched the same business day. Suitable for dermatology clinic retail, aesthetic practice dispensaries, and specialist skincare programme supply.\u003c\/em\u003e\u003c\/p\u003e\n\n\u003cscript type=\"application\/ld+json\"\u003e\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"FAQPage\",\n  \"mainEntity\": [\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What is SkinCeuticals C E Ferulic® Vitamin C Serum used for?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"SkinCeuticals C E Ferulic® Vitamin C Serum is a topical skincare product available from EMIS+ (emis.asia) in Singapore, applied to the skin as directed on the packaging. Individual results vary, and products should be chosen to suit your skin type and concerns.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"How do I use SkinCeuticals C E Ferulic® Vitamin C Serum?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Apply as directed on the product packaging. Introduce new products gradually and perform a patch test on a small area first, especially if you have sensitive or reactive skin. If irritation persists, stop use and consult a doctor or dermatologist (for example at the National Skin Centre or a private clinic in Singapore).\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Is SkinCeuticals C E Ferulic® Vitamin C Serum available without prescription in Singapore?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Yes. SkinCeuticals C E Ferulic® Vitamin C Serum is available from EMIS+ (emis.asia) without a prescription. For persistent or medical skin concerns, consult a dermatologist or your doctor.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Where can I buy SkinCeuticals C E Ferulic® Vitamin C Serum in Singapore?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"SkinCeuticals C E Ferulic® Vitamin C Serum is available from EMIS+ at emis.asia, Singapore's nurse-led medical and wellness supply store, with fast island-wide delivery. Bulk orders for clinics and care facilities are welcome — contact us at emis.asia\/pages\/contact.\"\n      }\n    }\n  ]\n}\n\u003c\/script\u003e","brand":"SkinCeuticals","offers":[{"title":"30 ml","offer_id":43041858027598,"sku":"635494363210","price":285.0,"currency_code":"SGD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3763\/2846\/files\/SkinCeuticals_C_E_Ferulic_Vitamin_C_Serum_607f613b-8345-4bdf-bc7a-1f2f67ea10b3.png?v=1767124935","url":"https:\/\/tw.emis.asia\/en\/products\/c-e-ferulic-vitamin-c-serum-drmsj","provider":"EMIS+","version":"1.0","type":"link"}